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KMID : 0922320170240010061
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Journal of Korean Academic Society of Home Care Nursing
2017 Volume.24 No. 1 p.61 ~ p.68
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The Influence of Disease Activity and Uncertainty on Anxiety and Depression in Patients with Ankylosing Spondylitis
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Lim Jong-Mi
Cho Ok-Hee
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Abstract
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Purpose: The purpose of this study was to understand how disease activity and uncertainty influence anxiety and depression in patients with ankylosing spondylitis
Methods: Participants were 125 patients with ankylosing spondylitis who had attended the rheumatology division of a university hospital. A structured questionnaire was used to assess disease activity, uncertainty, anxiety, and depression. The data gathered were analyzed using t-tests, ANOVAs, Pearson correlation coefficients, and a multiple regression.
Results: Differences were observed in anxiety based on job status, and in depression based on age, marriage, and job status. Uncertainty and disease activity predicted patients’ anxiety and explained 40% of the variance in this measure, and the relative influence of uncertainty (β=.38, p<.001) was larger than that of disease activity (β=.30, p<.001). Furthermore, uncertainty and disease activity predicted depression and explained 36% of the variance therein, and the relative influence of uncertainty (β=.27, p=.002) and disease activity (β=.27, p=.003) was similar.
Conclusion: This study confirmed that disease activity and uncertainty influenced anxiety and depression in patients with ankylosing spondylitis. Therefore, efforts to decrease anxiety and depression in patients with this condition must take into consideration disease activity when implementing nursing interventions and should include strategies to lower uncertainty.
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KEYWORD
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Ankylosing spondylitis , Disease activity , Uncertainty , Anxiety , Depression
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